Treatment of Elevated Cholesterol

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Treatment of elevated cholesterol.

As we age, cholesterol builds up in the arteries of the heart and neck, placing us at risk for heart attacks, strokes, and premature death. Treatment that lowers cholesterol in the blood has therefore become the cornerstone of prevention of future heart attack, stroke, and death, both in persons who definitely have heart disease and in those who are at risk of developing it in the future. Evide...

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Prevalence of Elevated Non-HDL Cholesterol among Patients with Diabetes in An Iranian Population

Background and Aims: Non-high density lipoprotein cholesterol (non-HDL-C), which reflects all cholesterol present in potentially atherogenic lipoprotein particles, might be a useful marker of atherosclerosis in diabetic subjects. In the present study, we evaluated the prevalence of high non-HDL-C in patients with dyslipidemia in diabetic and non-diabetic subjects following LDL-C assessment as t...

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Elevated Cholesterol and Bile Acid Synthesis

outputs in the normal child were 11.5 and 3.3 mg/kg per d, respectively. Thus, in comparison with the normal child, the patient with homozygous familial hypercholesterolemia had a marked increase in synthesis of cholesterol and bile acids. Although synthesis ofbile acids was high in this patient, the fraction of newly synthesized cholesterol converted into bile acids (4056%) was in the normal r...

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Cellular cholesterol efflux to plasma from proteinuric patients is elevated and remains unaffected by antiproteinuric treatment.

BACKGROUND Lipid derangements are assumed to contribute to the elevated cardiovascular risk in proteinuric patients. The impact of proteinuria on reverse cholesterol transport (RCT) is unknown. The first step in RCT, cellular cholesterol efflux to plasma, may be altered in proteinuria, consequent to changes in pre-beta high-density lipoprotein (HDL) formation and plasma phospholipid transfer pr...

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ژورنال

عنوان ژورنال: Circulation

سال: 2005

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.105.539106